Knee Osteoarthritis
Research Study
Research Study
Researchers at the University of Michigan want to examine the effects of cannabinoids CBD and THC on knee osteoarthritis pain. Join our compensated study today.
Study ID: HUM00180986 IRB: IRBMED Date Approved: 4/11/2024 Expiration Date: 4/10/2025
Conducted in Ann Arbor, MI
Compensation Provided
21-75 Years Old
Diagnosed with Knee Osteoarthritis
Fast Facts
MRI Eligible
Study Background
The goal of this study is to better understand how daily treatment with tetrahydrocannabinol (THC), cannabidiol (CBD), or the combination of CBD+THC affects knee osteoarthritis pain and other related symptoms.
We know that knee OA is painful and reduces quality of life. Our research team is dedicated to helping patients lead more comfortable and fulfilling lives by managing pain and other symptoms that come with knee OA.
Your participation may help health care providers better care for knee osteoarthritis patients in the future. Check eligibility today. Compensation provided.
We know that knee OA is painful and reduces quality of life. Our research team is dedicated to helping patients lead more comfortable and fulfilling lives by managing pain and other symptoms that come with knee OA.
Your participation may help health care providers better care for knee osteoarthritis patients in the future. Check eligibility today. Compensation provided.
Additional Information
The goal of this study is to better understand how daily treatment with tetrahydrocannabinol (THC), cannabidiol (CBD), or the combination of CBD+THC affects knee osteoarthritis pain and other related symptoms.
You may qualify for this study if you meet the following criteria.
Key Criteria:
Key Criteria:
- 21-75 years of age
- Diagnosed with knee osteoarthritis
- Chronic knee pain, moderate to severe knee pain for equal or greater than 6-month duration
- Willing to participate in a drug intervention
- No use of cannabis or CBD in the past month
- Able to undergo an MRI scan (i.e., no metal implants)
- Read and speak English
Participation involves 7 in-person visits and will last 18 weeks.
First, potential participants will complete a screening visit, including blood and urine tests, medical history, measuring vitals, demographic information, and a questionnaire about pain.
If eligible, participants will be randomly assigned to one of four different treatment groups that will receive an investigational study drug.
The study visits will include measuring vitals, blood and urine collection, questionnaires, sensory testing, and two MRI brain scans.
In addition, participants have the option to wear an activity watch for two weeks and complete a daily sleep/activity diary.
First, potential participants will complete a screening visit, including blood and urine tests, medical history, measuring vitals, demographic information, and a questionnaire about pain.
If eligible, participants will be randomly assigned to one of four different treatment groups that will receive an investigational study drug.
The study visits will include measuring vitals, blood and urine collection, questionnaires, sensory testing, and two MRI brain scans.
In addition, participants have the option to wear an activity watch for two weeks and complete a daily sleep/activity diary.
Study participants will be compensated up to $695 for their time.
There is no cost for you to participate in our research program.