Using Cocaine and Want to Stop OR in Treatment for Cocaine Use?
Researchers at Virginia Commonwealth University are investigating an FDA-approved medication that may help reduce cocaine use in individuals who are trying to quit. Join our research study today!
Conducted in Richmond, VA
25-65 Years Old
Eligible for an MRI
Fast Facts
Trying to Quit Using Cocaine
Study Background The study goal is to determine whether a daily skin patch that delivers Rotigotine, an FDA-approved medication, helps individuals reduce cocaine use in combination with individual or group therapy. Receiving Rotigotine as a treatment (in addition to other treatments) may also improve cognitive function in individuals receiving therapy for cocaine use disorder, helping them retain concepts better and maintain goals in recovery. Further research on cocaine use disorder treatments and join our study today! |
Additional Information
The purpose of this research study is to investigate whether transdermal Rotigotine, in addition to other treatments, can reduce cocaine use in individuals who are receiving treatment or who are interested in treatment for cocaine use disorder.
Once you pass the initial screens and are enrolled, this study involves:
- Eligibility screening: medical history, physical exam, blood & urine tests, breathalyzer, ECG, psychological screening interview, pregnancy test (if applicable), and questionnaires.
- Phenotyping & mock scan visit: urine drug screen, pregnancy test (if applicable), questionnaires, cognitive testing, and a mock MRI scanning session.
- Baseline visit: vitals, urine drug screen, pregnancy test (if applicable), breathalyzer, questionnaires, and 60-minute MRI scan while performing cognition tasks.
- Outpatient treatment visits: weeks 1-5, 2 study visits per week. Each visit will include a brief physical exam and tests, and each week you will be given a seven-dose pack of treatment patches OR placebo patches to use daily. You will also record your patch application every day in an app called Scene Health.
- Check-in visit: week 6. Brief physical exam, tests, and questionnaires.
- Follow-up assessment: week 6. Physical exam & tests, final drug use assessment, questionnaires & cognitive tasks, and a 60-minute MRI session.
- Safety/debrief visit: week 7. Brief physical exam, urine drug screen, breathalyzer, and questionnaires.
Compensation is provided for your participation.
There is no cost for you to participate in this study.