In Treatment for Cocaine Use Disorder?
Researchers at Virginia Commonwealth University are investigating an FDA-approved medication that may help reduce cocaine use in individuals who are already receiving treatment. Join our research study today!
Conducted in Richmond, VA
18-60 Years Old
Eligible for an MRI
Fast Facts
In Treatment For Cocaine Use Disorder
Study Background During this study, our researchers aim to evaluate if transdermal Rotigotine, an FDA-approved medication, in combination with individual or group therapy, helps individuals currently in treatment for cocaine use disorder reduce cocaine use. Receiving Rotigotine as a treatment (in addition to other treatments) may also improve cognitive function in individuals receiving therapy for cocaine use disorder, helping them retain concepts better and maintain goals in recovery. Further research on cocaine use disorder treatments and join our study today! |
Additional Information
The purpose of this research study is to investigate whether transdermal Rotigotine in addition to other treatments can reduce cocaine use in individuals who are currently receiving treatment for cocaine use disorder.
You may qualify for this study if you meet the following criteria.
Key Criteria:
Key Criteria:
- 18-60 years old
- Currently receiving treatment or scheduled to receive treatment for Cocaine Use Disorder
- No major medical, neurological, or psychotic conditions
- Eligible for an MRI
Once you pass the initial screens and are enrolled, this study involves:
- Eligibility screening: medical history, physical exam, blood & urine tests, breathalyzer, ECG, psychological screening interview, pregnancy test (if applicable), and questionnaires.
- Phenotyping & mock scan visit: urine drug screen, pregnancy test (if applicable), questionnaires, cognitive testing, and a mock MRI scanning session.
- Baseline visit: vitals, urine drug screen, pregnancy test (if applicable), breathalyzer, questionnaires, and 60-minute MRI scan while performing cognition tasks.
- Outpatient treatment visits: weeks 1-5, 2 study visits per week. Each visit will include a brief physical exam and tests, and each week you will be given a seven-dose pack of treatment patches OR placebo patches to use daily. You will also record your patch application every day in an app called Scene Health.
- Check-in visit: week 6. Brief physical exam, tests, and questionnaires.
- Follow-up assessment: week 6. Physical exam & tests, final drug use assessment, questionnaires & cognitive tasks, and a 60-minute MRI session.
- Safety/debrief visit: week 7. Brief physical exam, urine drug screen, breathalyzer, and questionnaires.
Compensation is provided for your participation.
There is no cost for you to participate in this study.