The Rembrandt Study
Researchers at the University of Pittsburgh want to understand why depression returns after treatment for some people and not others. Join our compensated study today!
Click Here to See if You are Eligible
Ages 60 and up with Depression
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Conducted in Pittsburgh, PA
Compensation Provided
mRI eligible
60+ Years Old
Fast Facts
current or history of depression
Study Background
Depression is a common condition in older adults. Symptoms of depression can include feeling sad or hopeless, feeling tired or not having energy, loss of interest in hobbies and activities, and changes in appetite. People with depression may also think of or attempt suicide.
Many older adults who have been successfully treated for depression will go on to experience another episode of depression in the future. Some evidence suggests that age-related
physical, biological, and social changes may play a role in the recurrence of depression, but researchers do not fully understand this relationship.
The purpose of this two-part study is to treat depression in older adults and better understand why some people experience a return of depression after successful treatment and some do not. Researchers hope their findings lead to better ways to identify, monitor, and treat older adults with depression who may be at a high risk for recurrence.
If you are an older adult who is currently suffering from depression, or has been treated for depression in the past, you may be eligible to participate in this study. We hope that this research will lead to better treatments in the future. Further research today and join our study!
Many older adults who have been successfully treated for depression will go on to experience another episode of depression in the future. Some evidence suggests that age-related
physical, biological, and social changes may play a role in the recurrence of depression, but researchers do not fully understand this relationship.
The purpose of this two-part study is to treat depression in older adults and better understand why some people experience a return of depression after successful treatment and some do not. Researchers hope their findings lead to better ways to identify, monitor, and treat older adults with depression who may be at a high risk for recurrence.
If you are an older adult who is currently suffering from depression, or has been treated for depression in the past, you may be eligible to participate in this study. We hope that this research will lead to better treatments in the future. Further research today and join our study!
Study Background Depression is a common condition in older adults. Symptoms of depression can include feeling sad or hopeless, feeling tired or not having energy, loss of interest in hobbies and activities, and changes in appetite. People with depression may also think of or attempt suicide. Many older adults who have been successfully treated for depression will go on to experience another episode of depression in the future. Some evidence suggests that age-related physical, biological, and social changes may play a role in the recurrence of depression, but researchers do not fully understand this relationship. The purpose of this two-part study is to treat depression in older adults and better understand why some people experience a return of depression after successful treatment and some do not. Researchers hope their findings lead to better ways to identify, monitor, and treat older adults with depression who may be at a high risk for recurrence. If you are an older adult who is currently suffering from depression, or has been treated for depression in the past, you may be eligible to participate in this study. We hope that this research will lead to better treatments in the future. Further research today and join our study! |
Click Here to See if You are Eligible
Additional Information
This study is aimed at learning more about depression and its recurrence after treatment in older adults.
You may qualify for a study if you meet the following criteria.
Eligibility Criteria:
Eligibility Criteria:
- Age 60+
- Current or past history of depression
- No mental health problems other than depression (or depression and anxiety)
- No drug or alcohol dependence within the last year
- Willing and able to have an MRI scan (no non-removable metal in your body; not claustrophobic)
This is a two-part study. During the first part of the study, if you are currently experiencing depression, you will undergo clinical evaluations and receive standard treatment using FDA-approved antidepressant medications. This will involve 2-5 visits over about 8-20 weeks. If your depression responds to treatment, you will then enter the second study phase.
If you have been treated for depression in the past and saw an improvement in your symptoms, you will go directly to phase two.
Participation in the second phase lasts for two years and involves 5-8 in-person visits and 6-9 phone calls. Eligible participants will undergo MRI scanning, memory
testing, and assessments. This study will not make any changes to
any antidepressant treatment you may be taking now and does not
specify what treatment you may receive in the future.
If you have been treated for depression in the past and saw an improvement in your symptoms, you will go directly to phase two.
Participation in the second phase lasts for two years and involves 5-8 in-person visits and 6-9 phone calls. Eligible participants will undergo MRI scanning, memory
testing, and assessments. This study will not make any changes to
any antidepressant treatment you may be taking now and does not
specify what treatment you may receive in the future.
Participants will be compensated up to $1,206 for their time.
There is no cost for you to participate in our research study.